[Safety of influenza vaccines in risk groups: analysis of adverse events following immunization reported in Valencian Community from 2005 to 2011].
Identifieur interne : 000164 ( Main/Exploration ); précédent : 000163; suivant : 000165[Safety of influenza vaccines in risk groups: analysis of adverse events following immunization reported in Valencian Community from 2005 to 2011].
Auteurs : Ana María Alguacil-Ramos [Espagne] ; Teresa Ma Garrigues-Pelufo ; Julio Muelas-Tirado ; Antonio Portero-Alonso ; Jordi Pérez-Panadés ; Jaime Fons-MartínezSource :
- Revista espanola de quimioterapia : publicacion oficial de la Sociedad Espanola de Quimioterapia [ 1988-9518 ] ; 2015.
Descripteurs français
- KwdFr :
- Adolescent (MeSH), Adulte (MeSH), Adulte d'âge moyen (MeSH), Douleur (étiologie), Enfant (MeSH), Espagne (épidémiologie), Exposition professionnelle (MeSH), Fatigue (étiologie), Femelle (MeSH), Grossesse (MeSH), Humains (MeSH), Jeune adulte (MeSH), Maladie chronique (épidémiologie), Mâle (MeSH), Obésité morbide (épidémiologie), Personnel de santé (statistiques et données numériques), Populations vulnérables (statistiques et données numériques), Risque (MeSH), Répartition par sexe (MeSH), Répartition par âge (MeSH), Sujet immunodéprimé (MeSH), Sujet âgé (MeSH), Vaccins antigrippaux (effets indésirables), Érythème (étiologie), Études transversales (MeSH).
- MESH :
- effets indésirables : Vaccins antigrippaux.
- statistiques et données numériques : Personnel de santé, Populations vulnérables.
- épidémiologie : Espagne, Maladie chronique, Obésité morbide.
- étiologie : Douleur, Fatigue, Érythème.
- Adolescent, Adulte, Adulte d'âge moyen, Enfant, Exposition professionnelle, Femelle, Grossesse, Humains, Jeune adulte, Mâle, Risque, Répartition par sexe, Répartition par âge, Sujet immunodéprimé, Sujet âgé, Études transversales.
- Wicri :
- geographic : Espagne.
English descriptors
- KwdEn :
- Adolescent (MeSH), Adult (MeSH), Age Distribution (MeSH), Aged (MeSH), Child (MeSH), Chronic Disease (epidemiology), Cross-Sectional Studies (MeSH), Erythema (etiology), Fatigue (etiology), Female (MeSH), Health Personnel (statistics & numerical data), Humans (MeSH), Immunocompromised Host (MeSH), Influenza Vaccines (adverse effects), Male (MeSH), Middle Aged (MeSH), Obesity, Morbid (epidemiology), Occupational Exposure (MeSH), Pain (etiology), Pregnancy (MeSH), Risk (MeSH), Sex Distribution (MeSH), Spain (epidemiology), Vulnerable Populations (statistics & numerical data), Young Adult (MeSH).
- MESH :
- chemical , adverse effects : Influenza Vaccines.
- geographic , epidemiology : Spain.
- epidemiology : Chronic Disease, Obesity, Morbid.
- etiology : Erythema, Fatigue, Pain.
- statistics & numerical data : Health Personnel, Vulnerable Populations.
- Adolescent, Adult, Age Distribution, Aged, Child, Cross-Sectional Studies, Female, Humans, Immunocompromised Host, Male, Middle Aged, Occupational Exposure, Pregnancy, Risk, Sex Distribution, Young Adult.
Abstract
OBJECTIVE
To evaluate reports of adverse events following influenza immunization by sex, risk and age groups in Valencian Community from 2005 to 2011.
METHODS
A pharmacoepidemiological descriptive cross-sectional observational study based on the reports of adverse events following immunization (AEFI) against influenza, registered through the Vaccination Information System (SIV) of Valencian Community from 1 January 2005 until 31 December 2011 was done.
RESULTS
During the study period 5,107,790 doses of vaccine against influenza were reported, with an AEFI incidence of 1.94 per 100,000 (95% CI 1.59 to 2.36), and 228,094 doses of vaccine for influenza A (H1N1) pdm09 (96.45 per 100,000, 95%CI 84.52-110.06). The 70.71% (70) and 64.55% (142), respectively, of AEFI were in women. The healthcare workers group had a higher reporting rate for seasonal influenza (25.35 per 100,000; 95%CI: 17.65-36.40) and for influenza A(H1N1) pdm09 (864.13 per 100,000; 95%CI 714.38-1044.93) during the study period.
CONCLUSIONS
Vaccines against influenza administered during the study had a high safety profile in both populations with disease risk and other susceptible target groups of vaccination. Adverse reactions reported during the study mostly coincide with those described in the summary of product characteristics of vaccines.
PubMed: 26200027
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first="Jaime" last="Fons-Martínez">Jaime Fons-Martínez</name></author></analytic><series><title level="j">Revista espanola de quimioterapia : publicacion oficial de la Sociedad Espanola de Quimioterapia</title><idno type="eISSN">1988-9518</idno><imprint><date when="2015" type="published">2015</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Adolescent (MeSH)</term><term>Adult (MeSH)</term><term>Age Distribution (MeSH)</term><term>Aged (MeSH)</term><term>Child (MeSH)</term><term>Chronic Disease (epidemiology)</term><term>Cross-Sectional Studies (MeSH)</term><term>Erythema (etiology)</term><term>Fatigue (etiology)</term><term>Female (MeSH)</term><term>Health Personnel (statistics & numerical data)</term><term>Humans (MeSH)</term><term>Immunocompromised Host (MeSH)</term><term>Influenza Vaccines (adverse effects)</term><term>Male (MeSH)</term><term>Middle Aged (MeSH)</term><term>Obesity, Morbid (epidemiology)</term><term>Occupational Exposure (MeSH)</term><term>Pain (etiology)</term><term>Pregnancy (MeSH)</term><term>Risk (MeSH)</term><term>Sex Distribution (MeSH)</term><term>Spain (epidemiology)</term><term>Vulnerable Populations (statistics & numerical data)</term><term>Young Adult (MeSH)</term></keywords><keywords scheme="KwdFr" xml:lang="fr"><term>Adolescent (MeSH)</term><term>Adulte (MeSH)</term><term>Adulte d'âge moyen (MeSH)</term><term>Douleur (étiologie)</term><term>Enfant (MeSH)</term><term>Espagne (épidémiologie)</term><term>Exposition professionnelle (MeSH)</term><term>Fatigue (étiologie)</term><term>Femelle (MeSH)</term><term>Grossesse (MeSH)</term><term>Humains (MeSH)</term><term>Jeune adulte (MeSH)</term><term>Maladie chronique (épidémiologie)</term><term>Mâle (MeSH)</term><term>Obésité morbide (épidémiologie)</term><term>Personnel de santé (statistiques et données numériques)</term><term>Populations vulnérables (statistiques et données numériques)</term><term>Risque (MeSH)</term><term>Répartition par sexe (MeSH)</term><term>Répartition par âge (MeSH)</term><term>Sujet immunodéprimé (MeSH)</term><term>Sujet âgé (MeSH)</term><term>Vaccins antigrippaux (effets indésirables)</term><term>Érythème (étiologie)</term><term>Études transversales (MeSH)</term></keywords><keywords scheme="MESH" type="chemical" qualifier="adverse effects" xml:lang="en"><term>Influenza Vaccines</term></keywords><keywords scheme="MESH" type="geographic" qualifier="epidemiology" xml:lang="en"><term>Spain</term></keywords><keywords scheme="MESH" qualifier="effets indésirables" xml:lang="fr"><term>Vaccins antigrippaux</term></keywords><keywords scheme="MESH" qualifier="epidemiology" xml:lang="en"><term>Chronic Disease</term><term>Obesity, Morbid</term></keywords><keywords scheme="MESH" qualifier="etiology" xml:lang="en"><term>Erythema</term><term>Fatigue</term><term>Pain</term></keywords><keywords scheme="MESH" qualifier="statistics & numerical data" xml:lang="en"><term>Health Personnel</term><term>Vulnerable Populations</term></keywords><keywords scheme="MESH" qualifier="statistiques et données numériques" xml:lang="fr"><term>Personnel de santé</term><term>Populations vulnérables</term></keywords><keywords scheme="MESH" qualifier="épidémiologie" xml:lang="fr"><term>Espagne</term><term>Maladie chronique</term><term>Obésité morbide</term></keywords><keywords scheme="MESH" qualifier="étiologie" xml:lang="fr"><term>Douleur</term><term>Fatigue</term><term>Érythème</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Adolescent</term><term>Adult</term><term>Age Distribution</term><term>Aged</term><term>Child</term><term>Cross-Sectional Studies</term><term>Female</term><term>Humans</term><term>Immunocompromised Host</term><term>Male</term><term>Middle Aged</term><term>Occupational Exposure</term><term>Pregnancy</term><term>Risk</term><term>Sex Distribution</term><term>Young Adult</term></keywords><keywords scheme="MESH" xml:lang="fr"><term>Adolescent</term><term>Adulte</term><term>Adulte d'âge moyen</term><term>Enfant</term><term>Exposition professionnelle</term><term>Femelle</term><term>Grossesse</term><term>Humains</term><term>Jeune adulte</term><term>Mâle</term><term>Risque</term><term>Répartition par sexe</term><term>Répartition par âge</term><term>Sujet immunodéprimé</term><term>Sujet âgé</term><term>Études transversales</term></keywords><keywords scheme="Wicri" type="geographic" xml:lang="fr"><term>Espagne</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><p><b>OBJECTIVE</b></p><p>To evaluate reports of adverse events following influenza immunization by sex, risk and age groups in Valencian Community from 2005 to 2011.</p></div><div type="abstract" xml:lang="en"><p><b>METHODS</b></p><p>A pharmacoepidemiological descriptive cross-sectional observational study based on the reports of adverse events following immunization (AEFI) against influenza, registered through the Vaccination Information System (SIV) of Valencian Community from 1 January 2005 until 31 December 2011 was done.</p></div><div type="abstract" xml:lang="en"><p><b>RESULTS</b></p><p>During the study period 5,107,790 doses of vaccine against influenza were reported, with an AEFI incidence of 1.94 per 100,000 (95% CI 1.59 to 2.36), and 228,094 doses of vaccine for influenza A (H1N1) pdm09 (96.45 per 100,000, 95%CI 84.52-110.06). The 70.71% (70) and 64.55% (142), respectively, of AEFI were in women. The healthcare workers group had a higher reporting rate for seasonal influenza (25.35 per 100,000; 95%CI: 17.65-36.40) and for influenza A(H1N1) pdm09 (864.13 per 100,000; 95%CI 714.38-1044.93) during the study period.</p></div><div type="abstract" xml:lang="en"><p><b>CONCLUSIONS</b></p><p>Vaccines against influenza administered during the study had a high safety profile in both populations with disease risk and other susceptible target groups of vaccination. Adverse reactions reported during the study mostly coincide with those described in the summary of product characteristics of vaccines.</p></div></front></TEI><pubmed><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">26200027</PMID><DateCompleted><Year>2016</Year><Month>05</Month><Day>02</Day></DateCompleted><DateRevised><Year>2015</Year><Month>07</Month><Day>23</Day></DateRevised><Article PubModel="Print"><Journal><ISSN IssnType="Electronic">1988-9518</ISSN><JournalIssue CitedMedium="Internet"><Volume>28</Volume><Issue>4</Issue><PubDate><Year>2015</Year><Month>Aug</Month></PubDate></JournalIssue><Title>Revista espanola de quimioterapia : publicacion oficial de la Sociedad Espanola de Quimioterapia</Title><ISOAbbreviation>Rev Esp Quimioter</ISOAbbreviation></Journal><ArticleTitle>[Safety of influenza vaccines in risk groups: analysis of adverse events following immunization reported in Valencian Community from 2005 to 2011].</ArticleTitle><Pagination><MedlinePgn>193-9</MedlinePgn></Pagination><Abstract><AbstractText Label="OBJECTIVE" NlmCategory="OBJECTIVE">To evaluate reports of adverse events following influenza immunization by sex, risk and age groups in Valencian Community from 2005 to 2011.</AbstractText><AbstractText Label="METHODS" NlmCategory="METHODS">A pharmacoepidemiological descriptive cross-sectional observational study based on the reports of adverse events following immunization (AEFI) against influenza, registered through the Vaccination Information System (SIV) of Valencian Community from 1 January 2005 until 31 December 2011 was done.</AbstractText><AbstractText Label="RESULTS" NlmCategory="RESULTS">During the study period 5,107,790 doses of vaccine against influenza were reported, with an AEFI incidence of 1.94 per 100,000 (95% CI 1.59 to 2.36), and 228,094 doses of vaccine for influenza A (H1N1) pdm09 (96.45 per 100,000, 95%CI 84.52-110.06). The 70.71% (70) and 64.55% (142), respectively, of AEFI were in women. The healthcare workers group had a higher reporting rate for seasonal influenza (25.35 per 100,000; 95%CI: 17.65-36.40) and for influenza A(H1N1) pdm09 (864.13 per 100,000; 95%CI 714.38-1044.93) during the study period.</AbstractText><AbstractText Label="CONCLUSIONS" NlmCategory="CONCLUSIONS">Vaccines against influenza administered during the study had a high safety profile in both populations with disease risk and other susceptible target groups of vaccination. Adverse reactions reported during the study mostly coincide with those described in the summary of product characteristics of vaccines.</AbstractText></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Alguacil-Ramos</LastName><ForeName>Ana María</ForeName><Initials>AM</Initials><AffiliationInfo><Affiliation>Ana Maria Alguacil Ramos, Dirección General de Salud Pública, Avd Cataluña nº21, 46020 Valencia, Spain. alguacil_ana@gva.es.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Garrigues-Pelufo</LastName><ForeName>Teresa Ma</ForeName><Initials>TM</Initials></Author><Author ValidYN="Y"><LastName>Muelas-Tirado</LastName><ForeName>Julio</ForeName><Initials>J</Initials></Author><Author ValidYN="Y"><LastName>Portero-Alonso</LastName><ForeName>Antonio</ForeName><Initials>A</Initials></Author><Author ValidYN="Y"><LastName>Pérez-Panadés</LastName><ForeName>Jordi</ForeName><Initials>J</Initials></Author><Author ValidYN="Y"><LastName>Fons-Martínez</LastName><ForeName>Jaime</ForeName><Initials>J</Initials></Author></AuthorList><Language>spa</Language><PublicationTypeList><PublicationType UI="D004740">English Abstract</PublicationType><PublicationType UI="D016428">Journal Article</PublicationType><PublicationType UI="D064888">Observational Study</PublicationType></PublicationTypeList><VernacularTitle>Seguridad de las vacunas antigripales en grupos de riesgo: análisis de las sospechas de reacciones adversas notificadas en Comunidad Valenciana entre 2005 y 2011.</VernacularTitle></Article><MedlineJournalInfo><Country>Spain</Country><MedlineTA>Rev Esp Quimioter</MedlineTA><NlmUniqueID>9108821</NlmUniqueID><ISSNLinking>0214-3429</ISSNLinking></MedlineJournalInfo><ChemicalList><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D007252">Influenza Vaccines</NameOfSubstance></Chemical></ChemicalList><CitationSubset>IM</CitationSubset><MeshHeadingList><MeshHeading><DescriptorName UI="D000293" MajorTopicYN="N">Adolescent</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D000328" MajorTopicYN="N">Adult</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D017677" MajorTopicYN="N">Age Distribution</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D000368" MajorTopicYN="N">Aged</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D002648" MajorTopicYN="N">Child</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D002908" MajorTopicYN="N">Chronic Disease</DescriptorName><QualifierName UI="Q000453" MajorTopicYN="N">epidemiology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D003430" MajorTopicYN="N">Cross-Sectional Studies</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D004890" MajorTopicYN="N">Erythema</DescriptorName><QualifierName UI="Q000209" MajorTopicYN="N">etiology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D005221" MajorTopicYN="N">Fatigue</DescriptorName><QualifierName UI="Q000209" MajorTopicYN="N">etiology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D005260" MajorTopicYN="N">Female</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D006282" MajorTopicYN="N">Health Personnel</DescriptorName><QualifierName UI="Q000706" MajorTopicYN="N">statistics & numerical data</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D006801" MajorTopicYN="N">Humans</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D016867" MajorTopicYN="N">Immunocompromised Host</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D007252" MajorTopicYN="N">Influenza Vaccines</DescriptorName><QualifierName UI="Q000009" MajorTopicYN="Y">adverse effects</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D008297" MajorTopicYN="N">Male</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D008875" MajorTopicYN="N">Middle Aged</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D009767" MajorTopicYN="N">Obesity, Morbid</DescriptorName><QualifierName UI="Q000453" MajorTopicYN="N">epidemiology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D016273" MajorTopicYN="N">Occupational Exposure</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D010146" MajorTopicYN="N">Pain</DescriptorName><QualifierName UI="Q000209" MajorTopicYN="N">etiology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D011247" MajorTopicYN="N">Pregnancy</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D012306" MajorTopicYN="N">Risk</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D017678" MajorTopicYN="N">Sex Distribution</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D013030" MajorTopicYN="N" Type="Geographic">Spain</DescriptorName><QualifierName UI="Q000453" MajorTopicYN="N">epidemiology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D035862" MajorTopicYN="N">Vulnerable Populations</DescriptorName><QualifierName UI="Q000706" MajorTopicYN="N">statistics & numerical data</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D055815" MajorTopicYN="N">Young Adult</DescriptorName></MeshHeading></MeshHeadingList></MedlineCitation><PubmedData><History><PubMedPubDate PubStatus="entrez"><Year>2015</Year><Month>7</Month><Day>23</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="pubmed"><Year>2015</Year><Month>7</Month><Day>23</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="medline"><Year>2016</Year><Month>5</Month><Day>3</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate></History><PublicationStatus>ppublish</PublicationStatus><ArticleIdList><ArticleId IdType="pubmed">26200027</ArticleId><ArticleId IdType="pii">alguacil</ArticleId></ArticleIdList></PubmedData></pubmed><affiliations><list><country><li>Espagne</li></country><region><li>Communauté valencienne</li></region></list><tree><noCountry><name sortKey="Fons Martinez, Jaime" sort="Fons Martinez, Jaime" uniqKey="Fons Martinez J" first="Jaime" last="Fons-Martínez">Jaime Fons-Martínez</name><name sortKey="Garrigues Pelufo, Teresa Ma" sort="Garrigues Pelufo, Teresa Ma" uniqKey="Garrigues Pelufo T" first="Teresa Ma" last="Garrigues-Pelufo">Teresa Ma Garrigues-Pelufo</name><name sortKey="Muelas Tirado, Julio" sort="Muelas Tirado, Julio" uniqKey="Muelas Tirado J" first="Julio" last="Muelas-Tirado">Julio Muelas-Tirado</name><name sortKey="Perez Panades, Jordi" sort="Perez Panades, Jordi" uniqKey="Perez Panades J" first="Jordi" last="Pérez-Panadés">Jordi Pérez-Panadés</name><name sortKey="Portero Alonso, Antonio" sort="Portero Alonso, Antonio" uniqKey="Portero Alonso A" first="Antonio" last="Portero-Alonso">Antonio Portero-Alonso</name></noCountry><country name="Espagne"><region name="Communauté valencienne"><name sortKey="Alguacil Ramos, Ana Maria" sort="Alguacil Ramos, Ana Maria" uniqKey="Alguacil Ramos A" first="Ana María" last="Alguacil-Ramos">Ana María Alguacil-Ramos</name></region></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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